CONCORD: Secondary Structure Prediction

CONCORD is a consensus-based method for protein secondary structure prediction utilizing several popular methods, including PSIPRED [1], DSC [2], GOR IV [3], Predator [4], Prof [5], PROFphd [6], and SSpro [7].

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Publication

    Y. Wei, J. Thompson and C. A. Floudas, CONCORD: A consensus method for protein secondary structure prediction via Mixed Integer Linear Optimization, Published online November 18, 2011, doi: 10.1098/rspa.2011.0514

References

  1. Jones, D. T. Protein secondary structure prediction based on position-specific scoring matrices. J. Mol. Biol. 1999, 292 (2), 195-202.
  2. King, R. D.; Saqi, M.; Sayle, R.; Sternberg, M. J. E. DSC: public domain protein secondary structure prediction. Bioinformatics 1997, 13 (4), 473-474. DOI: 10.1093/bioinformatics/13.4.473
  3. Garnier, J.; Gibrat, J. F.; Robson, B. GOR method for predicting protein secondary structure from amino acid sequence. Methods Enzymol 1996, 266, 540-543.
  4. Frishman, D.; Argos, P. Incorporation of non-local interactions in protein secondary structure prediction from amino acid sequence. Protein Eng. 1996, 9 (2), 133-142. DOI: 10.1093/protein/9.2.133
  5. Ouali, M.; King, R. D. Cascaded multiple classifiers for secondary structure prediction. Protein Sci. 2000, 9 (6), 1162-1176. DOI: 10.1110/ps.9.6.1162
  6. Rost, B. PredictProtein - internet prediction service. Columbia University, New York, 2000.
  7. Cheng, J.; Randall, A.; Sweredoski, M.; Baldi, P. SCRATCH: a Protein Structure and Structural Feature Prediction Server. Nucleic Acids Res. 2005, 33, 72-76.